The aim of this work was to study the incidence, diagnostics and clinical features of interstitial lung diseases (ILD) in the practical work of pulmonological and rheumatological departments of a multifield hospital Theanalysis included 565 case histories of the patients admitted to these departments in 2008-2012. The structure of ILD was elucidated along with the frequency of major clinical symptoms ofsarcoidosis and rheumatic diseases, the occurrence of clinico-morphological variants of ILD. Difficulties encountered in diagnostics of ILD and systemic scleroderma as well as their causes are discussed Resultsof the 5 year followup of 40 patients are presented.