In treating chronic bronchitis, the effect of 13 Herbs Anti-Cough-Dyspnea decoction was better than that of other traditional prescriptions such as Ephedria-almond decoction etc. The effective rate of this decoction in relieving cough, sputum, bronchial spasm and eliminating wheezing sound were 98.6%, 98.32%, 91.52% and 85.35% respectively. The total effective rate was 98%. The animal experiment revealed that the decoction was given to isolated trachea after medication for 30 min, the effective rate in easing bronchial spasm was 99.1 +/- 30.2%, which was two times than that of other prescriptions.