Effectiveness of bronchial thermoplasty in severe asthma in 'real life' patients compared with those recruited to clinical trials in the same centre

Ther Adv Respir Dis. 2015 Dec;9(6):267-71. doi: 10.1177/1753465815601332. Epub 2015 Aug 24.

Abstract

Published information on the effectiveness of bronchial thermoplasty (BT) for severe asthma in 'real life' patients is limited. We compared safety and efficacy outcomes 12 months post procedure in 10 clinic patients and 15 patients recruited to clinical trials of BT at the same centre. Baseline asthma severity was greater in the clinic group. Adverse events were similar. Clinical improvements occurred in 50% of the clinic patients compared with 73% of the research patients.

Keywords: asthma; bronchial thermoplasty; bronchoscopy.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adult
  • Anti-Asthmatic Agents / therapeutic use
  • Asthma / diagnosis
  • Asthma / physiopathology
  • Asthma / surgery*
  • Bronchi / physiopathology
  • Bronchi / surgery*
  • Bronchoscopy / adverse effects
  • Bronchoscopy / methods*
  • Catheter Ablation / adverse effects
  • Catheter Ablation / methods*
  • Clinical Trials as Topic / methods*
  • Female
  • Forced Expiratory Volume
  • Humans
  • Male
  • Middle Aged
  • Patient Selection*
  • Recovery of Function
  • Scotland
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome

Substances

  • Anti-Asthmatic Agents