Interferon gamma-induced protein-10 concentrations in children with previous tuberculosis infections and disease

Pediatr Infect Dis J. 2012 Oct;31(10):1089-91. doi: 10.1097/INF.0b013e3182611152.

Abstract

Interferon gamma-induced protein-10 is a diagnostic test for tuberculosis infection. There is no information on its concentrations over time. Interferon gamma-induced protein-10 was evaluated in 72 children formerly treated or in former contact with tuberculosis using Quantiferon Gold in-tube. Cases and contacts had similar interferon gamma-induced protein-10 concentrations. Concentrations varied with the tuberculin and interferon gamma release tests' concordance or discordance, and were independent of time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Biomarkers / blood*
  • Chemokine CXCL10 / blood*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant
  • Male
  • Time Factors
  • Tuberculosis / diagnosis*
  • Tuberculosis / immunology*

Substances

  • Biomarkers
  • CXCL10 protein, human
  • Chemokine CXCL10