Left ventricular function in children with sleep-disordered breathing

Am J Cardiol. 2005 Mar 15;95(6):801-4. doi: 10.1016/j.amjcard.2004.11.044.

Abstract

Severe obstructive sleep apnea in children leads to congestive heart failure. We studied the early changes in left ventricular function across a range of severity of the disorder. A dose-dependent decrease in diastolic function with increased severity of obstructive apnea was demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Blood Flow Velocity / physiology
  • Blood Pressure / physiology
  • Cardiac Volume / physiology
  • Child
  • Child, Preschool
  • Diastole / physiology
  • Echocardiography
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / physiopathology
  • Humans
  • Male
  • Mitral Valve / physiopathology
  • Myocardial Contraction / physiology
  • Oxygen / blood
  • Polysomnography
  • Reference Values
  • Risk Factors
  • Sleep Apnea, Obstructive / diagnosis*
  • Sleep Apnea, Obstructive / physiopathology
  • Systole / physiology
  • Ventricular Dysfunction, Left / diagnosis*
  • Ventricular Dysfunction, Left / physiopathology
  • Ventricular Function, Left / physiology

Substances

  • Oxygen