Dual infection with Streptococcus pneumoniae and Mycobacterium tuberculosis in HIV-seropositive patients with community acquired pneumonia

Int J Tuberc Lung Dis. 2003 Dec;7(12):1207-8.

Abstract

Pulmonary infections with more than one organism are common in human immunodeficiency virus (HIV) seropositive patients. We describe nine cases of dual infection with Streptococcus pneumoniae and Mycobacterium tuberculosis in HIV-seropositive patients presenting with community acquired pneumonia (CAP). It is important to exclude pulmonary tuberculosis in HIV-seropositive patients with CAP who fail to respond appropriately to initial antibiotic therapy, even if another etiological pathogen has been found.

MeSH terms

  • AIDS-Related Opportunistic Infections / complications*
  • AIDS-Related Opportunistic Infections / diagnosis
  • AIDS-Related Opportunistic Infections / drug therapy
  • Anti-HIV Agents / therapeutic use
  • Antitubercular Agents / therapeutic use
  • Community-Acquired Infections / complications*
  • Community-Acquired Infections / diagnosis
  • Community-Acquired Infections / drug therapy
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Mycobacterium tuberculosis / isolation & purification
  • Pneumonia, Pneumococcal / complications*
  • Pneumonia, Pneumococcal / diagnosis
  • Pneumonia, Pneumococcal / drug therapy
  • Prognosis
  • Retrospective Studies
  • Risk Assessment
  • Sampling Studies
  • Severity of Illness Index
  • South Africa
  • Streptococcus pneumoniae / isolation & purification
  • Treatment Outcome
  • Tuberculosis, Pulmonary / complications*
  • Tuberculosis, Pulmonary / diagnosis
  • Tuberculosis, Pulmonary / drug therapy

Substances

  • Anti-HIV Agents
  • Antitubercular Agents