Abstract
A case of allergic bronchopulmonary Aspergillosis (ABPA) complicating lung transplantation for cystic fibrosis is described. Control of ABPA was only achieved with 20 mg of prednisone and 600 mg of itraconazole per day. However, a prompt clinical and physiologic response was observed when nebulized amphotericin was introduced, which allowed prednisone to be reduced to 7.5 mg per day and, in time, all anti-fungal therapy to be withdrawn.
MeSH terms
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Administration, Inhalation
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Adult
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Amphotericin B / administration & dosage*
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Antifungal Agents / administration & dosage*
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Aspergillosis, Allergic Bronchopulmonary / diagnosis
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Aspergillosis, Allergic Bronchopulmonary / drug therapy*
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Cystic Fibrosis / surgery
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Drug Therapy, Combination
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Glucocorticoids / administration & dosage
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Humans
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Itraconazole / administration & dosage
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Lung Transplantation / adverse effects*
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Male
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Prednisone / administration & dosage
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Tomography, X-Ray Computed
Substances
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Antifungal Agents
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Glucocorticoids
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Itraconazole
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Amphotericin B
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Prednisone