Communications to the Editor

Mometason Furoate Levels

To the Editor:

I read with interest the article of Affrime et al (December 2000),¹ which concluded that mometasone furoate dry-powder inhaler at a dosage of 800 μg bid represents the lower limit for consistently detectable systemic effects. This would appear to be rather economical with the truth, as it was clearly evident from Figure 3 that the dosage 400 μg bid resulted in significant suppression of the serum cortisol area under the curve (AUC) 24 h after 7 days (p < 0.01), 14 days (p < 0.05), and 21 days