Chest
Clinical InvestigationsSleep and BreathingEffects of Humidification on Nasal Symptoms and Compliance in Sleep Apnea Patients Using Continuous Positive Airway Pressure
Section snippets
Subjects
Eligible patients were between 18 and 75 years old, had an OSA diagnosis (respiratory disturbance index [RDI] ≥ 10), and had not received CPAP treatment previously. Comorbid medical or psychological conditions were considered to be exclusion criteria only if the condition interfered with the patient's ability to successfully utilize CPAP. Exclusion criteria included wake resting pulse oximetric saturation < 90%, evidence of upper airway tract infection or flu-like symptoms at the time of
Patient Characteristics
Forty-seven patients were enrolled in the study. Nine patients were unable to complete the protocol. Two patients were dropped from the study at the time of CPAP titration. One patient titrated with cold passover humidity exhibited persistent central apneas, and one patient titrated with heated humidity exhibited poor sleep efficiency and a significant degree of sleep discontinuity. Definitive pressure settings could not be obtained for either patient. One patient receiving cold passover
Discussion
CPAP use with heated humidity, but not cold passover humidity, resulted in greater usage when compared to CPAP use without humidity. Specific side effects that compromised CPAP use, such as dry mouth or throat and dry nose, were experienced to a lesser degree during heated humidification, when compared to CPAP use with cold passover humidity or CPAP use without humidity. The patients were more satisfied with CPAP when it was used with either heated or cold passover humidity. However, the
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This research was supported by a grant from Fisher & Paykel Healthcare. Sullivan V Elite RTC machines and SCAN 2.01 compliancesoftware were provided by Res Med Corporation.