Chest
Volume 113, Issue 6, June 1998, Pages 1689-1694
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Special Report
Use of Guidelines in Treating Community-Acquired Pneumonia

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Study objectives

Guidelines for empiric treatment of community-acquired pneumonia (CAP) have been developed to assist in prescribing appropriate antimicrobials. We studied utilization of guidelines developed by the American Thoracic, Canadian Infectious Diseases, and Canadian Thoracic Societies (ATS, CIDS, and CTS, respectively), physicians' familiarity with them, reasons that prompt deviation from them, and their effects on clinical outcomes.

Design

Two-part observational study, with prospective and retrospective groups.

Setting

A 1, 100-bed, two-campus, tertiary-care teaching hospital.

Patients and participants

Patients admitted to the general medical ward who were being treated empirically for CAP and housestaff who provided their care.

Interventions

Medical residents reported on patients admitted to the hospital with CAP. The charts of all unreported patients admitted with CAP over the same period were reviewed. Measurements and results: One hundred twenty-two patients were prospectively described and another 130 patients were identified retrospectively. There was no difference in guidelines adherence between the prospective and retrospective groups (81% compared with 80%; p=0.94). Deviation occurred most commonly in suspected aspiration. When physicians believed that they were following guidelines, this was true in 88%. When physicians believed that they were deviating, they were actually adhering in 46%. Guidelines adherence did not alter in-hospital mortality (12% compared with 14%, p=0.92) or length of hospitalization (median, 6 days for both groups).

Conclusions

ATS/CIDS/CTS guidelines for empiric treatment of CAP are widely used in our institution. Future amendments should address aspiration more explicitly. Residents' familiarity with them could be improved. Beneficial effects on outcomes remain unproven.

Section snippets

MATERIALS AND METHODS

The study setting is a 1, 100-bed, two-campus, tertiary-care teaching hospital (The Toronto Hospital). Inpatient medical care is provided by teams of housestaff, each of one second- or third-year (senior) medical resident, two first-year residents, and two medical students. General medical patients admitted to this institution are referred by the emergency physician to the on-call housestaff. They are assessed for hospital admission by one of the housestaff members, and initial treatment plans

RESULTS

Two hundred fifty-five eligible patients were admitted to the hospital over the study period. One hundred twenty-two (48%) had questionnaires completed prospectively by housestaff, and 130 of the remaining 133 had their charts reviewed retrospectively (3 charts could not be located). Data on 252 patients were therefore available for analysis. Demographic, comorbidity, and guidelines adherence data comparing the two groups are summarized in Table 1. There were no significant differences in sex

DISCUSSION

This study, which assessed the utilization of the ATS/CIDS/CTS guidelines for empiric treatment of CAP at a tertiary-care center, provides some insight into how the guidelines might be usefully modified and also attempts to address their effects on clinical outcome. The only similar published study of which we are aware studied outpatients and did not assess reasons for guidelines deviation.17

We found the guidelines to be widely used in our institution, with similar adherence rates of 81% and

ACKNOWLEDGMENTS

We wish to thank Drs. Moira Kapral and Howard Leong-Poi, all the attending staff in the Clinical Teaching Units and housestaff at the Toronto Hospital during the academic year 1995 to 1996 for making this project possible.

References (16)

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Reprint requests: Charles K. N. Chan, MD, FCCP, 10 EN-220, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4

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