Chest
Volume 140, Issue 5, November 2011, Pages 1107-1108
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Bronchiectasis in Patients With COPD: A Distinct COPD Phenotype?

https://doi.org/10.1378/chest.11-1484Get rights and content

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    Whether COPD associated bronchiectasis is a distinct COPD phenotype, cannot be concluded from our study as we did not compare COPD patients without bronchiectasis. However, our data add to previous research suggesting that COPD with bronchiectasis is different from bronchiectasis in other circumstances [19–21]. The higher mortality might be attributed to the fact that these patients have more severe and more frequent exacerbations, higher degree of airway inflammation, lower lung function and increased colonization [19,22,23].

  • Validity and reliability of the St. George's respiratory questionnaire in assessing health status in patients with chronic pulmonary aspergillosis

    2013, Chest
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    This study showed that COPD was the most common and effective underlying comorbidity with CPA. Since both CPA1,2,5 and COPD34–36 are chronic, progressive, inflammatory, pulmonary diseases, a possibility of an existing interaction between these two diseases can be suggested. Perhaps “synergistic” destruction of pulmonary tissue and inflammation would contribute to the high SGRQ score of those who had both diseases.

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Financial/nonfinancial disclosures: The author has reported to CHEST the following conflicts of interest: Dr O'Donnell has received research funding for clinical trials from Bronchiectasis Registry/COPD Foundation; Gilead Sciences, Inc; Bayer Corporation; Pharmaxis, Inc; and Insmed Incorporated. She has received consultant fees from Gilead Sciences, Inc; Bayer Corporation; and Hill-Rom, Inc.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).

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