Chest
Clinical Investigations: Bronchial ReactivityIndices of Morbidity and Control of Asthma in Adult Patients Exposed to Environmental Tobacco Smoke
Section snippets
Material and Methods
We studied 200 never-smoker patients with asthma of 15 to 50 years of age attending the chest outpatient clinic of our institute during a 1-year period during their follow-up visits. Patients were classified into group 1 or 2 depending on the history of absence or presence of ETS exposure. Enrollment of group 2 patients had to be continued for about 3 more months after group 1 to match the number of patients. At the time of the study, their conditions were fairly stable without any significant
Results
The mean age and disease duration of the two groups were comparable (Table 1). While mean VC (percent predicted) was almost similar, the forced expiratory flows such as FEV1 and FEF25-75% were lower (p<0.01) in group 2 than group 1 patients (Table I).
The number of patients requiring ED visits, hospitalization, and given parenteral injections of bronchodilators at home was similar in the two groups, but more patients in group 2 required daily maintenance bronchodilators and intermittent
Discussion
Although there is information available in children, there is a paucity of data on adverse effects of ETS exposure on lung function and disease severity in adults. Passive smoking in 276 children with asthma was positively associated with ED visits, but not hospitalization.10 The estimated mean annual increase in ED visits attributable to the presence of one or more smokers in the household was 1.34 ± 0.5, an increase of 63 percent over nonsmoking households.10 Passive smoking may also increase
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