Chest
Volume 104, Issue 4, October 1993, Pages 1294-1296
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Selected Reports
Bronchiolitis Obliterans Organizing Pneumonia Caused by Plasmodium vivax Malaria

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A 64-year-old woman developed a relapse of Plasmodium vivax malaria followed by a rapidly progressive diffuse patchy pulmonary process. Open lung biopsy specimen showed bronchiolitis obliterans organizing pneumonia (BOOP). After corticosteroid therapy was initiated, there was both clinical and radiographic improvement. This is believed to be the first reported association of BOOP with malaria.

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Case Report

A 64-year-old Indian woman was admitted to our institution with a four-day history of intermittent fevers and recurrent nausea associated with coffee ground vomiting. She related a history of travel to New Delhi, India, one year prior to hospital admission without receiving malaria prophylaxis. She reported having been treated for malaria several times in the past, and had received chloroquine prophylaxis on her previous travels to New Delhi.

At the time of hospital admission, her blood pressure

Discussion

We report the findings in a patient with cough, increasing dyspnea, and acute diffuse patchy pulmonary infiltrates found on chest radiograph that progressed despite treatment of P vivax malaria. Pulmonary complications of malaria are rare and have been described almost exclusively in patients with falciparum malaria.2 Little reference could be found in the English literature in regard to pulmonary involvement in vivax malaria infections. The only pulmonary manifestation of vivax malaria found

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