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ORIGINAL RESEARCHINTERVENTIONAL PULMONOLOGYElectromagnetic Navigation Diagnostic Bronchoscopy in Peripheral Lung Lesions
Section snippets
Materials and Methods
Eighty-nine patients underwent ENB at our two centers between February 2005 and August 2006. Inclusion criteria were subjects above the age of 18 years, who signed informed consent forms and were candidates for elective bronchoscopy. They all had evidence of peripheral lung lesions or solitary pulmonary nodules with no evidence of endobronchial pathology. Pregnant patients and those with implantable pacemakers or defibrillators were excluded. The institutional review boards of both of the
Results
Ninety-two peripheral lung lesions were biopsied in the 89 subjects, of whom 39 (44%) were female. The mean age was 67 ± 12 years (age range, 29 to 95 years). The mean size of lesions was 24 ± 8 mm (range, 10 to 58 mm); the mean number of forceps biopsies performed was 5 ± 1 (range, 0 to 11). A single patient had no forceps biopsies because the navigation error was 31 mm despite multiple attempts. This was attributed to the possible absence of a bronchus leading to the lesion. The bronchial
Discussion
In this largest series to date, we have shown that ENB can be used as an independent bronchoscopic technique without the need for fluoroscopy when compared with other available studies. There was no compromise in the diagnostic yield and no increased risk of pneumothorax. This yield was attributable to the small registration error (< 5 mm) and navigation error (< 10 mm) that occurred. Our pneumothorax rate (2 of 89 patients; 2%) compares favorably with those of preceding studies,35 in which the
ACKNOWLEDGMENT
Dr. Roger Davis from Department of Medicine, Beth Israel Deaconess Medical Center (Boston, MA) assisted with the statistical analysis. Robert Garland from Interventional Pulmonology, Beth Israel Deaconess Medical Center (Boston, MA) assisted with data collection.
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Cited by (276)
Single Institution Evaluation of Electromagnetic Navigation Bronchoscopy for Diagnosis of Pulmonary Lesions
2024, Journal of Bronchology and Interventional Pulmonology
A portion of these data has been accepted as an abstract for the 2007 American Thoracic Society International Conference.
The locatable sensor probes at both Thoraxklinik and Beth Israel Deaconess Medical Center were provided free of charge by superDimension/Bronchus. superDimension/Bronchus has supported CME courses at the Thoraxklinik Heidelberg and Harvard University through unrestricted educational grants. Dr. Ernst was a member of the Scientific Advisory Board of superDimension/Bronchus and had been reimbursed for time and travel expenses related to that function. Dr. Ernst also had stock options, which have been returned in the past. Dr. Ernst was not involved in the consenting process of patients. Drs. Eberhardt, Anantham, Herth, and Feller-Kopman have reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.