Proceedings from the Consensus Conference on the Treatment of Viral Respiratory Infection-Induced Asthma in Young ChildrenViruses and asthma: Inception, exacerbation, and possible prevention☆
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Leukotriene receptor antagonist attenuated airway inflammation and hyperresponsiveness in a double-stranded RNA-induced asthma exacerbation model
2017, Allergology InternationalCitation Excerpt :Viral infections in the respiratory tract are the most common triggers of an acute asthma exacerbation.1
Serious Early Childhood Wheezing After Respiratory Syncytial Virus Lower Respiratory Tract Illness in Preterm Infants
2010, Clinical TherapeuticsCitation Excerpt :In this theory, no single factor dominates any other in determining outcome. Although the strongest association between viral lower respiratory tract infection and subsequent development of wheezing has been noted with RSV, there have been reports of other viral infections, such as rhinovirus, influenza virus, and parainfluenza virus, that triggered subsequent wheezing.28–30 One approach to delineating whether the pathway is causal or RSV-specific would be to demonstrate a reduction in long-term airway morbidity by reducing RSV in infancy.
Changes in weather and the effects on pediatric asthma exacerbations
2009, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Currently, 9 million US children younger than 18 years have been diagnosed as having asthma.4,5 Viral infections,6 tobacco smoke exposure,7 aeroallergens,8 and air pollutants9 have been shown to trigger pediatric asthma exacerbations. Parents and patients often attribute worsening asthma symptoms and exacerbations to “changes in the weather.”
The role of viruses in the development and exacerbation of atopic disease
2009, Annals of Allergy, Asthma and ImmunologyCitation Excerpt :Articles were selected for their relevance to viruses and their role in asthma. In reviewing the literature, we noted that there are essentially 3 avenues of viral asthma research: data supporting a role for viruses in the development of asthma, data focused on the role of viruses in asthma exacerbations, and data supporting a role of viruses in causing atopy.2 Evidence favoring a causative role for viral infections in asthma development includes studies focused on specific viruses, as well as several epidemiologic studies that have documented a role for viral exposure factors, such as day-care and family size.
RESPIRATORY SYNCYTIAL VIRUS
2009, Feigin and Cherry's Textbook of Pediatric Infectious Diseases, Sixth EditionInfluenza vaccination and childhood asthma
2008, Vacunas
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Supported by National Institutes of Health grants 1PO1AI50500, 2P50H L56396, and 1RO1HL61879.