How does air pollution affect asthma and allergic rhinitis? Particulate and gaseous pollution drive proallergic inflammation through the generation of oxidative stress, which is regulated by individual genetic susceptibility.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Diesel exhaust particles increase nasal symptoms and IL-17A in house dust mite-induced allergic mice
Scientific Reports Open Access 11 August 2021
-
Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s
Allergy, Asthma & Clinical Immunology Open Access 01 July 2020
-
Association between exposure to traffic-related air pollution and pediatric allergic diseases based on modeled air pollution concentrations and traffic measures in Seoul, Korea: a comparative analysis
Environmental Health Open Access 14 January 2020
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Heinrich, J. & Wichmann, H.E. Curr. Opin. Allergy Clin. Immunol. 4, 341–348 (2004).
National Air Pollutant Emission Trends (US Environmental Protection Agency, 1997).
Bernstein, J.A. et al. J. Allergy Clin. Immunol. 114, 1116–1123 (2004).
Takizawa, H. Curr. Opin. Allergy Clin. Immunol. 4, 355–359 (2004).
Diaz-Sanchez, D., Tsien, A., Fleming, J. & Saxon, A. J. Immunol. 158, 2406–2413 (1997).
Fahy, O. et al. J. Immunol. 168, 5912–5919 (2002).
Diaz-Sanchez, D., Garcia, M.P., Wang, M., Jyrala, M. & Saxon, A.J. Allergy Clin. Immunol. 104, 1183–1188 (1999).
Chen, L.L. et al. Chest 125, 2328–2335 (2004).
Xiao, C.G., Wang, M., Li, N., Loo, J.A. & Nel, A.E. J. Biol. Chem. 278, 50781–50790 (2003).
Todokoro, M. et al. Inflammation 28, 105–114 (2004).
Gilliland, F.D. et al. Am. J. Respir. Crit. Care Med. 166, 457–463 (2002).
London, S.J. et al. J. Natl. Cancer Inst. 85, 1246–1252 (1995).
Gilliland, F.D., Li, Y-F., Saxon, A. & Diaz-Sanchez, D. Lancet 363, 119–125 (2004).
Romieu, I. et al. Thorax 59, 8–10 (2004).
Kleeberger, S.R., Reddy, S., Zhang, L.Y. & Jedlicka, A.E. Am. J. Respir. Cell Mol. Biol. 22, 620–627 (2000).
Hollingsworth, J.W. et al. Am. J. Respir. Crit. Care Med. 170, 126–132 (2004).
Shore, S.A., Schwartzman, I.N., Le Blanc, B., Murthy, G.G. & Doerschuk, C.M. Am. J. Respir. Crit. Care Med. 164, 602–607 (2001).
Yang, I.A. et al. Am. J. Respir. Crit. Care Med. 171, 171–176 (2004).
Bayley, J.P., Ottenhoff, T.H. & Verweij, C.L. Genes Immun. 5, 315–329 (2004).
David, G.L. et al. Am. J. Respir. Crit. Care Med. 168, 1199–1204 (2003).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Saxon, A., Diaz-Sanchez, D. Air pollution and allergy: you are what you breathe. Nat Immunol 6, 223–226 (2005). https://doi.org/10.1038/ni0305-223
Issue Date:
DOI: https://doi.org/10.1038/ni0305-223
This article is cited by
-
Diesel exhaust particles increase nasal symptoms and IL-17A in house dust mite-induced allergic mice
Scientific Reports (2021)
-
Association between exposure to traffic-related air pollution and pediatric allergic diseases based on modeled air pollution concentrations and traffic measures in Seoul, Korea: a comparative analysis
Environmental Health (2020)
-
Comparison of allergens and symptoms in patients with allergic rhinitis between 1990s and 2010s
Allergy, Asthma & Clinical Immunology (2020)
-
Atmospheric particulate matter adhesion onto pollen: a review
Aerobiologia (2020)
-
Allergien und Umwelteinflüsse
Allergo Journal (2019)
