Abstract
The Paediatric Asthma Quality of Life Questionnaire (PAQLQ), developed by Juniper etal., assesses the impact of asthma on children's daily life. It contains 23 items, covering three dimensions: symptoms, activities limitation and emotional function. Aims: To develop an equivalent Spanish version of the PAQLQ, and to assess its measurement characteristics. Methods: The forward and back-translation method was used for the adaptation. A longitudinal study (assessments at the 1st and 5th weeks), with patients from the emergency and outpatient departments of three Spanish hospitals, was designed to test the properties of the new adapted version. At each visit, a trained interviewer administered the PAQLQ, a Global Index of Change and a General Health Perception scale. The Peak Expiratory Flow Rate (PEFR) was also recorded daily, together with symptoms, during the prior week. Results: Ninety-nine patients (66.7% males, 42.4% suffering an exacerbation, mean age of 11.3years) with the following types of asthma were evaluated: mild intermittent (31.3%), mild persistent (36.4%), moderate persistent (29.3%) and severe persistent (3%). At the 1st visit, the mean pre-bronchodilator %PEFR was 87.3%. The Cronbach's α ranged from 0.86 to 0.95. As expected, correlations between the PAQLQ scores, and the Asthma Control Score (0.53–0.67), the General Health Perception (0.34–0.55), and the %PEFR (0.44–0.55) were moderate. The PAQLQ scores remained unchanged in stable patients while increased significantly in those showing improvements. Conclusions: After a standard cross-cultural adaptation process, the Spanish version of the PAQLQ has shown to be equivalent to the original, with similar internal consistency reliability, validity and sensitivity to clinical changes.
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References
ISAAC Study Group. Worldwide variation in prevalence of symptoms of asthma, allergic rhinocojunctivitis and atopic eczema: ISAAC. Lancet 1998; 351(9111): 1225–1232.
Wilson I, Cleary P. Linking clinical variables with health-related quality of life: A conceptual model of patient outcomes. JAMA 1995; 273(1): 59–65.
Guyatt GH, Juniper EF, Feeny DH, Ferrie PJ, Griffith LE. Children and adult perceptions of childhood asthma. Pediatrics 1997; 99(2): 165–168.
Bender BG. Measurement of quality of life in pediatric asthma clinical trials. Ann Allergy Asthma Immunol 1996; 77(6): 438–447.
Pedersen S. What are the goals of treating pediatric asthma? Pediatric Pulmonol 1997; Suppl 15: 22–26.
National Asthma Education and Prevention Program. Guidelines for the diagnosis and management of asthma. Expert Panel Report II. National Institutes of Health, Lung and Blood Institutes. NIH 1997; 97: 40–51.
Bauman LJ. Discussant section. Am J Respir Crit Care Med 1994; 149: 40–43.
Editorial. Quality of life and clinical trials, Lancet 1995; 346: 1–2.
Fitzpatrick R, Fletcher A, Gore S, Jones D, Spiegelhalter D, Cox D. Quality of life measures in health care. I. Applications and issues in assessment. Br Med J 1992; 305: 1074–1077.
Fletcher A, Gore S, Jones D, Fitzpatrick R, Spiegelhalter D, Cox D. Quality of life measures in health care. II. Design, analysis and interpretation. Br Med J 1992; 305: 1145–1148.
Spiegelhalter D, Gore S, Fitzpatrick R, Fletcher A, Jones D, Cox D. Quality of life measures in health care. III. Br Med J 1992; 305: 1205–1209.
Guillemin F, Bombardier C, Beaton D. Cross-cultural adaptation of health-related quality of life measures: Literature review and proposed guidelines. J Clin Epidemiol 1993; 46(12): 1417–1432.
Hunt SM, Alonso J, Bucquet D, Niero M, Wiklund I, McKenna S. Cross-cultural adaptation of health measures. Health Policy 1991; 19: 34–44.
Juniper EF, Guyatt GH, Feeny DH, Ferrie PJ, Griffith LE, Townsend M. Measuring quality of life in children with asthma. Qual Life Res 1996; 5: 35–46.
Juniper EF, Guyatt GH, Willan A, Griffith LE. Determining a minimal important change in a disease-specific quality of life questionnaire. J Clin Epidemiol 1994; 47: 81–87.
Sanjuás C, Alonso J, Sanchís J, Casan P, Broquetas JM, Ferrie PJ. Cuestionario de calidad de vida en pacientes con asma: La versión española del asthma quality of life questionnaire. Arch Bronconeumol 1995; 31(5): 219–226.
American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease and asthma. Am Rev Resp Dis 1987; 136(1): 225–244.
Ferrés J. Comparison of two nebulized treatments in wheezing infants. Eur Resp J 1988; 1(suppl): 306.
Juniper EF, Kline PA, Vanzeileghem MA, Ramsdale EH, O'Byrne PM, Hargreave FE. Effect of long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness and clinical asthma severity in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990; 142: 832–836.
SPSS, Inc. SPSS X User's Guide, 2nd edition. Chicago: McGraw-Hill, 1986.
Nunnally JC, Bernstein IH. Psychometric Theory, 3rd edition. New York, NY: McGraw-Hill, 1994.
Howard KL, Forehand GC. A method for correcting itemtotal correlations for the effect of relevant item inclusion. Educ Psychol Meas 1962; 22: 731–735.
Hays RD, Hayashi T, Carson S, Ware JE. User's Guide for the Multitrait Analysis Program (MAP). Santa Monica, CA: RAND, 1988.
Townsend M, Feeny DH, Guyatt GH, et al. Evaluation of the burden of illness for paediatric asthmatic patients and their parents. Ann Allergy 1991; 67(4): 403–408.
Fritz GK, Klein RB, Overholser JC. Accuracy of symptom perception in childhood asthma. J Dev Behav Pediatr 1990; 11: 69–72.
Juniper EF. How important is quality of life in paediatric asthma? Pediatric Pulmonol 1997; Suppl 15: 17–21.
Juniper EF, Guyatt GH, Feeny DH, Griffith LE, Ferrie PJ. Minimum skills required by children to complete health-related quality of life instruments for asthma: Comparison of measurement properties. Eur Res J 1997; 10(10): 2285–2294.
Osman L, Silverman M. Measuring quality of life for young children with asthma and their families. Eur Resp J 1996; 9(Suppl 21): S35–S41.
Pedersen S, Hansen OR. Budesonide treatment of moderate and severe asthma in children: A dose-response study. J Allergy Clin Immunol 1995; 1: 29–33.
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Tauler, E., Vilagut, G., Grau, G. et al. The Spanish version of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ): Metric characteristics and equivalence with the original version. Qual Life Res 10, 81–91 (2001). https://doi.org/10.1023/A:1016622519987
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DOI: https://doi.org/10.1023/A:1016622519987