Asthma and lower airway diseaseThe airway microbiome in patients with severe asthma: Associations with disease features and severity
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Supported by Genentech (to H.B.), the National Institutes of Health/National Heart, Lung, and Blood Institute (HL105572 to Y.J.H.), and the Sandler Family Foundation (to H.B.).
Disclosure of potential conflict of interest: Y. J. Huang has received research support from the National Institutes of Health (NIH). S. Nariya has received research support from the NIH/National Heart, Lung, and Blood Institute (NHLBI). J. M. Harris is employed by Genentech/Roche and receives stock/stock options as part of his compensation. S. V. Lynch has received research support from Genentech, the National Institutes of Allergy and Infectious Diseases, the NHLBI, the National Center for Complementary and Alternative Medicine, Pfizer, the Cystic Fibrosis Foundation, the Sloan Foundation, Janssen, and the Broad Foundation; is a board member for Second Genome; has consultant arrangements with Janssen, Novartis, Boston Consulting Group, and Regeneron; has received payment for lectures from the American Thoracic Society and the American Academy of Allergy, Asthma & Immunology; holds patents US Patent 7,687,474 B2: “Nitroreductase Enzymes,” EP 2393515 A1: Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection, WO 2012027302 A2: Systems and methods for detecting antibiotic resistance, and WO 2013155370 A1: Sinusitis diagnostics and treatments; has received royalties from Kalobios; and has received payment for development of educational presentations from Georgia Regents University. D. F. Choy is employed by Genentech, holds Roche stock and options, and is a coinventor of pending patents related to biomarker and therapeutic strategies in asthma through Genentech. J. R. Arron is employed by Genentech and has stock/stock options with Roche Holdings. H. Boushey has had consultant arrangements with Merck, GlaxoSmithKline, Genentech, Kalbios, Pharmaxis, and Johnson & Johnson; has received research support from GlaxoSmithKline and Genentech; has received payment for lectures from the Allergy, Asthma, and Immunology Foundation of Northern California and Breathe California; and has received royalties from the McGraw-Hill Companies.