Asthma and lower airway disease
Sexual dimorphism: Is it relevant to steroid resistance or asthma control?

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      Collectively, these findings could suggest that women with psychological morbidity experience less benefit from glucocorticoid therapy than do men. Indeed, a number of studies have suggested that there may be a sex difference in corticosteroid response (reviewed by Hunninghake and Gold75), but have conceded that more study is needed. Nonetheless, our data suggest that asthma with psychological morbidity should be examined in a sex-specific manner.

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    Disclosure of potential conflict of interest: D. R. Gold has received research support from the National Institutes of Health; G. M. Hunninghake has declared he has no conflicts of interest.

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    Copyright © 2009 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.