Original InvestigationSodium Nitrite Improves Exercise Hemodynamics and Ventricular Performance in Heart Failure With Preserved Ejection Fraction
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Key Words
cardiac output
nitrate
pressure
stroke volume
Abbreviations and Acronyms
BP
blood pressure
Cao2 − Cvo2
arteriovenous oxygen content difference
cGMP
cyclic guanosine monophosphate
CO
cardiac output
HFpEF
heart failure with preserved ejection fraction
LV
left ventricular
NO
nitric oxide
PA
pulmonary artery
PCWP
pulmonary capillary wedge pressure
PVR
pulmonary vascular resistance
RAP
right atrial pressure
SV
stroke volume
SVR
systemic vascular resistance
Vo2
oxygen consumption
VE/Vco2
ventilatory efficiency
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This study was supported by a grant from the Mayo Clinic Division of Cardiovascular Diseases. Dr. Borlaug receives research support from Aires Pharmaceuticals for a separate study examining the use of inhaled nitrite in patients with HFpEF. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
Copyright © 2015 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.