MethodEvaluation of Global and Regional Right Ventricular Systolic Function in Patients With Pulmonary Hypertension Using a Novel Speckle Tracking Method
Section snippets
Methods and Results
Patients with pulmonary hypertension (pulmonary artery systolic pressure >35 mm Hg) on 2-dimensional echocardiography and Doppler and age- and gender-matched control subjects (3:1 ratio) who underwent complete conventional echocardiographic examinations from July 2003 to April 2005 using digital acquisition on an Acuson ultrasound system (Siemens Medical Solutions USA, Inc., Mountain View, California) were screened for inclusion. The study was approved by the Institutional Review Board of
Discussion
The present study demonstrates that global and regional systolic function of the right ventricle can be quantitated simultaneously by a novel automated speckle-tracking method. Along with the determination of global indexes, this method provides 2-dimensional-derived regional tissue velocity, strain, and strain rate that are angle independent, allowing the differentiation of normal controls from patients with various degrees of pulmonary hypertension. To our knowledge, the right ventricle has
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This study was supported by an investigator-initiated research grant received from Siemens Medical Solutions USA, Inc., Mountain View, California.