ArticlesRandomised trial of thiacetazone and rifampicin-containing regimens for pulmonary tuberculosis in HIV-infected Ugandans
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Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches
2018, Biomedicine and PharmacotherapyCitation Excerpt :Such systems can not only improve the patient compliance but also minimize the risk of toxicity and other unwanted effects associated with the chemotherapy treatment. Various controlled drug delivery systems include microspheres, polymeric nanoparticles, liposomes, niosomes, liquid crystals, solid lipid nanoparticles, polymeric micelles, dendrimers, nanoemulsion, nanosuspension, silica nanoparticles, and microparticles [2–6,13–18]. Table 1 represents the opportunities of nano drug delivery over the conventional approach for the treatment of tuberculosis.
Nevirapine versus efavirenz for patients co-infected with HIV and tuberculosis: A systematic review and meta-analysis
2014, International Journal of Infectious DiseasesCitation Excerpt :The overall rates of favorable response to ATT were comparable between studies, with no significant differences between groups. A rifampin-containing regimen has been recommended by the WHO for the treatment of TB in patients infected with HIV due to its more favorable outcomes than non-rifampin treatments.33 ART is also important for the treatment of TB, as viral suppression is necessary for the restoration of Mycobacterium tuberculosis-specific CD4+ T cell responses.34
Paediatric use of second-line anti-tuberculosis agents: A review
2012, TuberculosisCitation Excerpt :Thiacetazone was used widely to treat TB prior to the advent of HIV. Severe, life-threatening Stevens Johnson reactions were associated with thiacetazone use in HIV-infected adults186,187 and children.188 Although it is contraindicated only in HIV-infected individuals, it is now rarely available in most countries.
Tuberculosis and Atypical Mycobacterial Infections
2011, Tropical Infectious Diseases: Principles, Pathogens and PracticeTuberculosis and Atypical Mycobacterial Infections
2011, Tropical Infectious DiseasesTreatment outcomes of patients co-infected with HIV and tuberculosis who received a nevirapine-based antiretroviral regimen: A four-year prospective study
2010, International Journal of Infectious DiseasesCitation Excerpt :Although rifabutin has fewer problematic drug–drug interactions, it is not available in many countries, particularly not in resource-limited settings. However, rifamycin-containing regimens are preferred in the treatment of HIV and TB co-infection as they result in a lower relapse rate and better outcome.7 According to current HIV treatment guidelines, including Thai guidelines, efavirenz-based ART is a preferred first-line regimen in HIV/TB co-infected patients who are receiving a rifampin-containing regimen, because of the lesser drug–drug interactions when compared to nevirapine or PIs.8
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Participants are listed at the end of the article.