Original ArticlesEvaluation of fluorine-18-fluorodeoxyglucose whole body positron emission tomography imaging in the staging of lung cancer
Section snippets
Patients and methods
All patients referred to one surgeon for the consideration of resection for lung cancer in the period were studied. Ninety-seven patients were studied from November 1992 to July 1995. Follow-up continued to July 1996.
Entry criteria included (1) biopsy proved lung cancer (n = 84) or strong suspicion of cancer on clinical and CT criteria (n = 13); and (2) operability by clinical and CT staging with TNM stage 3a or less or equivocal evidence on other imaging of metastatic disease.
Results
Ninety-seven patients (64 men) were included in the study. The mean age was 63.3 years (range, 36 to 77 years). There was histologically proved malignancy in 84 patients before PET imaging, whereas 13 had suspicion of cancer, which was subsequently proved in 11. Histologic subtypes are summarized in Table 1.
Comment
A recent consensus statement from the American Thoracic Society and European Respiratory Society [17] on the pretreatment evaluation of non-small cell carcinoma of the lung suggests that PET is in its early stages of development and not readily available outside academic centers and therefore, at present, has little role to play in the management of this group of patients. This contrasts heavily with the suggestion by Gambhir and colleagues [14] that incorporation of PET into an assessment of
Acknowledgements
We thank Paul Seed for assistance with statistical analysis and the staff of The Clinical PET Centre for their expertise and the staff of the South East Thames Cancer Registry Office. Dr Catherine Saunders was assisted by the Bernie Amos Travelling Fellowship, Westmead Hospital.
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