Original articleThe influence of diagnostic access bias on the epidemiology of sarcoidosis: A population-based study in Rochester, Minnesota, 1935–1984☆
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Post-9/11 sarcoidosis in WTC-exposed firefighters and emergency medical service workers
2017, Respiratory MedicineCitation Excerpt :First, there is no agreed-upon baseline rate of sarcoidosis in the US. Published incidence and prevalence rates of sarcoidosis in non-WTC-exposed populations, which are often used as comparison rates for WTC-exposed, are highly variable and population dependent, based on race/ethnicity, geography [6,7], socioeconomic status and access to healthcare [8]. The access to care issue is of particular importance in sarcoidosis as a substantial proportion of cases (30–50% by various estimates) are asymptomatic [9], of which a significant proportion resolve spontaneously over time, leading to an unknown amount of undetected and unreported disease.
Sarcoidosis of the peripheral nervous system
2013, Handbook of Clinical NeurologyCitation Excerpt :An accurate estimate of the prevalence or incidence of sarcoidosis is probably not available. The reasons for this are: lack of consistent disease criteria; variability of disease presentation, and lack of sensitive and specific diagnostic tests, resulting in under recognition and misdiagnosis of the disease (Hennessy et al., 1988). Significant heterogeneity in disease presentation and severity occurs among different ethnic and racial groups.
Sarcoidosis and testicular cancer: A case series and literature review
2010, Urologic Oncology: Seminars and Original InvestigationsCitation Excerpt :Epidemiological studies of sarcoidosis and malignancy have potential confounding factors. It is known that the majority of cases of sarcoidosis are subclinical and that populations with access to diagnostic imaging have a higher rate of a diagnosis of sarcoidosis [10]. Imaging of patients with malignancy is therefore more likely to yield a diagnosis of sarcoidosis.
Autoimmune T cell responses to antigenic peptides presented by bronchoalveolar lavage cell HLA-DR molecules in sarcoidosis
2009, Clinical ImmunologyCitation Excerpt :Previously, it has been reported that sarcoidosis more commonly occurred in people who had been in contact with the disease before diagnosis (e.g., by contact with household members, colleagues at work and close friends) [29]. Studies have also reported an increased prevalence of sarcoidosis in health care workers, especially nurses [29,30], although those studies may be subject to diagnostic access bias since health care workers are more likely to have routine screening chest radiographs that would detect asymptomatic sarcoidosis [31]. It is also noteworthy that the two patients with the highest anti-vimentin reactivity both had extrapulmonary disease manifestations (skin and neurological, respectively).
Epidemiological features of Turkish patients with sarcoidosis
2009, Respiratory MedicineCitation Excerpt :Second method includes cases with definite diagnosis. However, it is thought that the real incidence rate should be higher than that of calculated as cases with definite diagnosis, because 31–68% of patients diagnosed with chest X-ray screening were asymptomatic.25,27,39–41 The case number of the autopsy studies are 10 times greater than the numbers of other methods.
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This investigation was supported in part by research grant AR30582 from the National Institutes of Health.