Original contributionBiological effects of diesel exhaust particles (DEP). III. Pathogenesis of asthma like symptoms in mice
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2019, Archives of Biochemistry and BiophysicsVesicular acetylcholine transport deficiency potentiates some inflammatory responses induced by diesel exhaust particles
2019, Ecotoxicology and Environmental SafetyCitation Excerpt :Alterations in the extracellular matrix components (Araujo et al., 2008), airway smooth muscle hypertrophy (James et al., 2012), goblet cell hypertrophy and hyperplasia with increased mucus production are known features of lung remodeling. These alterations are involved in several lung diseases including inflammation induced by air pollution (Ishihara and Kagawa, 2002; Sagai et al., 1996). To determine the effect of DEP instillation in lung remodeling processes we measured collagen and elastic fibers content in lung alveolar septa of VAChT-KD mice and WT controls.
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2018, Food and Chemical ToxicologyCitation Excerpt :The particulate phase of diesel exhaust (DE) is thought to contribute to the increased prevalence of acute and chronic airway diseases (de Kok et al., 2006; Li et al., 2003). It is clear that DE causes lung cancer, allergic rhinitis, and bronchial asthma–like diseases (McClellan, 1987; Muranaka et al., 1986; Sagai et al., 1996; Steenland et al., 1998). DE is a complex mixture of gaseous and particulate components.
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