Economic appraisal of asthma and COPD care: A literature review 1980–1991
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2007, Journal of Allergy and Clinical ImmunologyCitation Excerpt :A weighted average taken from the 3 adult trials of subjects with asthma estimated an improvement in health status (AQLQ) of 7.2%.28 In a report focusing on asthma, Molken et al44 observed that an 8.8% relative change in health status (AQLQ) was associated with a 0.9% change in preference based HRQOL (standard gamble). Thus our base-case analysis assumption of a preference-based HRQOL improvement of 0.9% in association with omalizumab treatment is consistent with the published literature.
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2000, ChestCitation Excerpt :Because implementation of clinical practice guidelines can be costly,26 managed care organizations may be reluctant to adopt a specific guideline if it is not accompanied by evidence that doing so yields significant health gains in return for added expenditure. There is very little literature documenting the cost-effectiveness of most medical interventions for COPD.27 Because guideline implementation programs can be costly, it may be difficult for managed care organizations to justify allocating scarce resources toward aggressive implementation programs for COPD relative to other chronic diseases in which the cost-effectiveness of treatments is known.