Other clinical studyInhibition of nitric oxide synthesis in the forearm arterial bed of patients with advanced cirrhosis☆,☆☆
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Cited by (81)
Pathophysiology of Sodium Retention and Wastage
2013, Seldin and Geibisch's The KidneyPathophysiology of Sodium Retention and Wastage
2012, Seldin and Giebisch's The Kidney: Physiology and PathophysiologyIncreased EETs participate in peripheral endothelial dysfunction of cirrhosis
2012, Prostaglandins and Other Lipid MediatorsCitation Excerpt :These hemodynamic alterations participate in the pathophysiology of portal hypertension which is responsible for the complications of cirrhosis: ascites, hepatorenal syndrome, esophageal varices, encephalopathy. Vasodilatation is present mainly in the mesenteric circulation of cirrhotic patients [2], while peripheral vasodilatation is still debated [3–9]. The alterations of peripheral circulation have been studied with different techniques giving different results.
Muscle circulation contributes to hyperdynamic circulatory syndrome in advanced cirrhosis
2008, Journal of HepatologyCitation Excerpt :Thus, it is conceivable that the vasodilation developing in advanced cirrhosis also involves the muscle districts: a statistically significant inverse correlation between femoral artery blood flow indicized by muscle mass and PVRi was found in patients, but not in healthy control subjects. This is in line with what was reported in conscious cirrhotic rats without ascites and hyperdynamic circulatory syndrome [41], and fully support data provided by the evaluation of forearm blood flow of cirrhotic patients by venous occlusion plethysmography [7–10]. Indeed, it should be pointed out that such a technique expresses the results of flow corrected for the amount of tissue, and, in this respect, provides an assessment that mimic what we performed in the present study.
Physiology and Pathophysiology of Sodium Retention and Wastage
2008, Seldin and Giebisch's The KidneyPhysiology and Pathophysiology of Sodium Retention and Wastage
2007, Seldin and Giebisch's The Kidney: Physiology & Pathophysiology 1-2
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This work was supported by a grant from La delegation a la Recherche Clinique de l'Assistance Publique-Hôpitaux de Paris (CRC 930202).
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Partial results from this study have been already published as an abstract at the 3rd International Meeting on “Biology of Nitric Oxide” in Cologne, Germany, October 1993 (Endothelium 1993;1: S89).