Combined clinical basic science seminarBrain dysfunction in mild to moderate hypoxia☆
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2022, Trends in NeurosciencesAbnormal brain oxygen homeostasis in an animal model of liver disease
2022, JHEP ReportsCitation Excerpt :In this study, we observe brain hypoperfusion at time points corresponding to previous reports of cognitive task performance impairment.10,29 We rely on the logical extension that a reduction in availability of metabolic substrates will lead to neuronal dysfunction manifesting neuropsychological impairment.51 Supporting the results of our study, Clément et al.50 recently demonstrated that in HE the brain, which is already compromised (decreased oxygenation and metabolic dysregulation), becomes susceptible to hypotensive insults resulting in neuronal cell death.
Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis
2020, Journal of Sport and Health Science
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This study was supported by Grants NS 15649, NS 03346, NS 15125, NS 16994, AA03883 and the Winifred Masterson Burke Relief Foundation.
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From the Department of Neurology, Cornell University Medical College, New York, New York, and the Dementia Research Program, Burke Rehabilitation Center, White Plains, New York.