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Pulmonary Mycobacterium xenopi Infection in AIDS Patients Treated with HAART in Hungary

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Abstract

Reported here are three cases of pulmonary Mycobacterium xenopi infection that occurred in AIDS patients in Hungary shortly after starting highly active antiretroviral therapy. In this country, Mycobacterium xenopi is the most common nontuberculous mycobacterial species causing pulmonary mycobacterial infections. Cases of pulmonary Mycobacterium xenopi disease have been described in patients infected with the human immunodeficiency virus infection and in patients with other immunodeficiencies; however, only limited information is currently available concerning the connection between nontuberculous Mycobacterium infection and AIDS in Hungary. This report thus adds useful information regarding the diagnosis, clinical course, and treatment regimens of Mycobacterium xenopi infections in AIDS patients.

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Acknowledgements

We wish to thank S. Dávid and T. Fodor of the Korányi National Institute for Tuberculosis and Lung Diseases, Mycobacteria Reference Laboratory, Budapest, Hungary, for identifying the mycobacterial isolates, D.van Soolingen and colleagues of the National Institute of Public Health and the Environment, National Mycobacteria Reference Laboratory, Bilthoven, the Netherlands, for the sequence analysis, Y.M. Hale and colleagues of the Bureau of Laboratories, Florida Department of Health, Jacksonville, Florida, USA, for performing high-performance liquid chromatography on the isolates.

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Correspondence to J. Szlávik.

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Szlávik, J., Sárvári, C. Pulmonary Mycobacterium xenopi Infection in AIDS Patients Treated with HAART in Hungary. Eur J Clin Microbiol Infect Dis 22, 701–703 (2003). https://doi.org/10.1007/s10096-003-1018-z

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