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Rescue hypothermia for refractory hypercapnia

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Abstract

Hypothermia may reduce the CO2 production by decreasing the metabolism of the cooled tissue. We describe the first clinical use of hypothermia to lower hypercarbia in a case of bronchiolitis related respiratory failure unresponsive to maximal respiratory support. In this case, hypothermia allowed sparing the use of extracorporeal life support. Conclusion Hypothermia might be useful for severe acute respiratory failure unresponsive to aggressive respiratory support.

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References

  1. Aslami H, Binnekade JM, Horn J, Huissoon S et al (2010) The effect of induced hypothermia on respiratory parameters in mechanically ventilated patients. Resuscitation 81:1723–1725

    Article  PubMed  Google Scholar 

  2. Ball MK, Hillman NH, Kallapur SG et al (2010) Body temperature effects on lung injury in ventilated preterm lambs. Resuscitation 81:749–754

    Article  PubMed  Google Scholar 

  3. Bellinger DC, Wypij D, du Plessis AJ et al (2001) Developmental and neurologic effects of α-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 121:374–383

    Article  PubMed  CAS  Google Scholar 

  4. De Luca D, Cogo P, Zecca E et al (2011) Intrapulmonary drug administration in neonatal and paediatric critical care: a comprehensive review. Eur Respir J 37:678–689

    Article  PubMed  Google Scholar 

  5. Pietrini D, Piastra M, Luca E, et al. (2012) Neuroprotection and hypothermia in infants and children. Curr Drug Targets 13:925–935

    Google Scholar 

  6. Polderman KH (2009) Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med 37:S186–S202

    Article  PubMed  Google Scholar 

  7. Ventre K, Haroon M, Davison C (2006) Surfactant therapy for bronchiolitis in critically ill infants. Cochrane Database Syst Rev 3: CD005150

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Conflicts of interest

Authors have neither conflict of interest nor any financial relationship to disclose.

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Authors and Affiliations

  1. Pediatric Intensive Care Unit, Department of Emergency and Intensive Care, University Hospital “A. Gemelli”, Catholic University of the Sacred Heart, Rome, Italy

    Domenico Pietrini, Francesca Vitale, Silvia Maria Pulitanò, Giorgio Conti, Aldo Mancino, Marco Piastra, Daniele De Luca & Daniele De Luca

  2. General Intensive Care Unit, Department of Emergency and Intensive Care, University Hospital “A. Gemelli”, Catholic University of the Sacred Heart, Rome, Italy

    Mariano Pennisi

Authors
  1. Domenico Pietrini
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  2. Mariano Pennisi
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  3. Francesca Vitale
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  4. Silvia Maria Pulitanò
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  5. Giorgio Conti
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  6. Aldo Mancino
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  7. Marco Piastra
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  8. Daniele De Luca
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Corresponding author

Correspondence to Daniele De Luca.

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Pietrini, D., Pennisi, M., Vitale, F. et al. Rescue hypothermia for refractory hypercapnia. Eur J Pediatr 171, 1855–1857 (2012). https://doi.org/10.1007/s00431-012-1769-6

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  • DOI: https://doi.org/10.1007/s00431-012-1769-6

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