Summary
In 29 (20.3%) of the 143 subjects exposed for a mean period of 19.1 years to carbon black dust, pneumoconiosic lesions, forms p and q, were radiologically detected. Carbon black pneumoconiosis is often accompanied by generalized or limited emphysema and scintigraphically detected disturbances of lung perfusion. Tuberculous pleuropulmonary sequalae but no active specific lesions were noted in 27.2% of the patients. Histologic investigation performed in one patient emphasized a diffuse emphysema and a slight but extended collagenous reaction. A statistically significant increase of serum IgA and decrease of IgM were found.
Résumé
Les auteurs ont constanté chez 29 sujets sur 143 (20.3%) exposés au noir de fumée, des lésions de pneumoconiose du type p et q. La durée moyenne d'exposition a été de 19.1 ans. La pneumoconiose au noir de fumée est fréquement associée à l'emphysème généralisé ou circonscrit et à des troubles de la perfusion pulmonaire décelable par la scintigraphie. Les séquelles pleuro-pulmonaires tuberculeuses ont eu une fréquence de 27.2%, les lésions tuberculeuses actives étant absenteq. Du point de vue histopathologique on a signalé, dans un cas autopsié, un emphysème diffus et une réaction collagéneuse réduite mais systématique. Du côte immunologique, on a constanté une augmentation des valeurs d'IgA et la baisse des valeurs d'IgM, statistiquement significatives.
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Cocarla, A., Cornea, G., Dengel, H. et al. Pneumoconiose au noir de fumée. Int. Arch Occup Environ Heath 36, 217–228 (1976). https://doi.org/10.1007/BF00378276
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DOI: https://doi.org/10.1007/BF00378276