Short CommunicationsPROGNOSTIC VALUE OF CYTOKINES IN SIRS GENERAL MEDICAL PATIENTS
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Cited by (86)
Impact of cytokines levels and interleukin 6 (-634 C>G) polymorphism on clinical outcomes in patients with sepsis
2020, Meta GeneCitation Excerpt :A single sepsis marker is incapable of promoting all these benefits, which requires the determination of molecules related to the inflammatory and immunosuppressive responses. The prognostic scores APACHE II (Acute Physiology and Chronic Health Evaluation II) and Sepsis-Related Organ Failure Assessment (SOFA) consider some clinical and laboratory findings and are used in ICUs for analyzing disease severity, thus predicting patient mortality (Rodríguez-Gaspar et al., 2001; Khwannimit et al., 2018). In the immune system, interferon (INF)-γ, tumor necrosis factor (TNF), and interleukins (IL; for example, IL2, IL4, IL6, and IL10) are crucial cytokines that act against infections and inflammatory processes (Lees, 2015; Mehta et al., 2018; Park et al., 2011; Atanasovska-Stojanovska et al., 2011; Brown et al., 2016).
Thrombocytopenia in critically ill patients with severe sepsis/septic shock: Prognostic value and association with a distinct serum cytokine profile
2016, Journal of Critical CareCitation Excerpt :On the contrary, in our study, we did not observe any significant correlation between ANC and serum cytokine levels meaning that ANC is not a marker of the severity of the inflammatory process. Previous studies examined peripheral blood cytokine levels in patients with sepsis, in an effort to identify biomarkers helping in prognostic stratification and in clinical management of critically ill patients [23-26]. Recent studies focused on the significance of serum suPAR levels in predicting hospital mortality in patients with sepsis [27-30].
Treatment with a neutralising anti-rat interleukin-17 antibody after multiple-trauma reduces lung inflammation
2015, InjuryCitation Excerpt :Recently, numerous studies [1,2] focus on trauma have shown that multiple trauma (for example: burn, high energy trauma, low energy trauma in elders, and so on) is associated with the development of systemic inflammatory response syndrome and strongly correlated with Multiple Organ Dysfunction Syndrome (MODS).
The immune response after stimulation with wall components of gram-positive bacteria and fungi
2014, Immunology Letters
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Correspondence to: Francisco Santolaria, Servicio de Medicina Interna, Hospital Universitario de Canarias, Universidad de La Laguna, Tenerife, Spain. E-mail:[email protected]