Abstract
Background: The disease severity in chronic obstructive pulmonary disease (COPD) can be evaluated in multidimensional system with the BODE index. Higher scores indicate a higher risk of death. In addition, measures of respiratory and peripheral muscle strength are important for prognosis in COPD.
Aim: To investigate relationship between BODE index, respiratory and peripheral muscle strength in COPD.
Methods: Twenty-five stable COPD patients (63.84±4.90years,13M,12F) were included. BODE index score was calculated according to FEV1, body mass index, dyspnea (Modified Medical Research Council Dyspnea Scale-mMRC), 6 minute walk test distance. Pulmonary function using a spirometer, peripheral muscle strength (hand grip) using a hand dynamometer, inspiratory and expiratory muscle strength (MIP, MEP) using a mouth pressure device were evaluated.
Results: BODE index score was negatively correlated with age (r=0.436, p=0.038), FVC (%) (r=0.650, p=0.001), FEV1/FVC (r=0.628, p=0.002), PEF (%) (r=0.706, p<0.001), FEF25-75 (%) (r=0.652, p=0.001), hand grip strength (r=0.597, p=0.004), MIP (r=0.591, p=0.008), MEP (r=0.638, p=0.003).
Conclusions: According to the results of this study, respiratory and peripheral muscle strength was related to the disease severity in COPD. Improvements in respiratory and peripheral muscle strength may bring about increased survival.
Footnotes
Cite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 280.
This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2020