CRISPR screening in primary human lung fibroblasts and small airway epithelial cells identifies novel targets to reduce cellular senescence with potential to treat both COPD and IPF
Johan Mattsson, Jenna Bradley, Pooja Sharma, Leire Escudero-Ibarz, Bairu Zhang, Chen Qian, Patrick O’Shea, Catherine Wrench, Maria Karlsson, Catherine Overed-Sayer, Isabel Rosa, James Pilling, Stephanie Constantinou, Lambert Montava Garriga, Valentina Quarantotti, Hui Sun Leong, Chang Kim, Elissavet Kentepozidou, Ceri Wiggins, Roxane Paulin, Laura Rosenberg, Davide Gianni, Henric Olsson
European Respiratory Journal Sep 2023, 62 (suppl 67) PA1233; DOI: 10.1183/13993003.congress-2023.PA1233