Table 1– Patient characteristics at baseline#
Female32 (36)
Age yrs35 (27–47)
Weight kg58.3 (49.6–66.7)
Length cm170 (162–175)
BMI kg·m−220.1 (17.9–23.0)
Ethnicity
 Caucasian29 (32.6)
 Asian17 (19.1)
 African41 (46.1)
 Other2 (2.3)
Duration of hospital stay days62.5 (35–112.3)
Tuberculosis
 Localisation
  Pulmonary67 (75.3)
  Extrapulmonary29 (32.6)
  Other5 (5.6)
Diagnosis
 Sputum60 (67.4)
 Other¶,+29 (32.6)
Resistance pattern
 Fully susceptible54 (60.7)
 MDR20 (22.5)
 INH resistant2 (2.3)
 INH and ethambutol resistant1 (1.1)
 Unknown12 (13.5)
Comorbidity
 Chronic pre-existent liver disease5 (5.6)
 Chronic renal dysfunction1 (1.1)
 Epilepsy1 (1.1)
 Diabetes mellitus10 (11.2)
 HIV co-infection10 (11.2)
 Alcohol abuse8 (9.0)
  • Data are presented as n (%) or median (interquartile range). #: n=89. BMI: body mass index; MDR: multidrug resistant; INH: isoniazid. : diagnosis based on clinical conditions, chest radiograph, histology and/or response to therapy. +: in 29 cases, diagnosis is based on clinical conditions, chest radiograph, histology and/or response to therapy; in 17 out of 29 patients the resistance pattern was determined at a later stage.