Table 2– Comparison of early responses to bronchoscopic lung volume reduction in survivors and nonsurvivors
Nonsurvivor at 6 yrsSurvivor at 6 yrsp-value
Subjects n811
ΔSWT m17.5±6520.9±950.9
ΔDL,CO mmol·min−1·kPa−10.11±0.40.46±0.60.2
ΔRV L-0.01±0.4-0.62±1.20.37
ΔTLC L-0.17±0.28-0.31±0.550.53
ΔFRC L-0.26±0.41-0.49±0.860.53
Δendurance time s26.5±148133±1720.17
ΔFEV1 L-0.01±0.170.18±0.20.06
Δisotime EELV L-0.16±0.56-0.61±1.00.31
ΔSGRQ-0.6±10.6-0.1±8.40.9
Atelectasis0 (0)5 (45)0.026#
  • Data are presented as mean±sd or n (%), unless otherwise stated. Endurance time refers to performance on a cycle ergometer at 80% of peak workload. p-values are for unpaired t-tests. δ: change in; SWT: shuttle walk test; DL,CO: diffusing capacity of the lung for carbon dioxide; RV: residual volume; TLC: total lung capacity; FRC: functional residual capacity; FEV1: forced expiratory volume in 1 s; EELV: end-expiratory lung volume; SGRQ: St George’s Respiratory Questionnaire total score. #: Chi-squared test.