Table 1– Results for the three single-nucleotide polymorphisms (SNPs) that remained significantly associated with overall, acute or chronic sarcoidosis after Bonferroni correction for multiple testing
dbSNPLocusChrPositionA1A2Unaffected controlsSarcoidosis
OverallAcuteChronic
MAFMAFOR (95% CI)p-valueMAFOR (95% CI)p-valueMAFOR (95% CI)p-value
rs11209026IL23R167478546AG0.070.050.71 (0.59–0.85)6.71×10−20.060.84 (0.64–1.09)>10.040.63 (0.50–0.79)1.79×10−2
rs120350821q24.31171165000CT0.390.421.15 (1.06–1.25)3.73×10−10.461.36 (1.21–1.54)2.34×10−40.401.07 (0.97–1.18)1
rs916977HERC21526186959AG0.110.131.30 (1.15–1.48)1.44×10−20.141.35 (1.13–1.62)3.49×10−10.131.29 (1.11–1.50)1
  • dbSNP: SNPs from the database at http://www.ncbi.nlm.nih.gov/projects/SNP/ Chr: chromosome; A: allele; MAF: minor allele frequency; UNAFF: unaffected controls. p-values are Bonferroni-corrected. Bold represents statistically significant results.