Table 1– Demographic characteristics, toxic habits, comorbidity, vaccination and prior empirical treatment

Characteristics	Value
Patients n	685
Age yrs	66.5±17.4
Sex F/M n	240/445 (35/65)
Current smoker	161 (23.6)
Alcohol excess	65 (9.5)
Comorbidity
COPD	135 (19.7)
CNS disorder	141 (20.7)
Diabetes	129 (18.9)
Heart failure	123 (18)
Renal failure	36 (5.3)
Liver disease	23 (3.4)
Prior vaccination
Influenza	299 (43.6)
Anti-pneumococcal	111 (16.2)
Prior antibiotic treatment	233 (34.1)

Data are presented as mean±sd or n (%), unless otherwise indicated. F: female; M: male; COPD: chronic obstructive pulmonary disease; CNS: central nervous system.