Table 1– Characteristics of metalworking fluid-associated hypersensitivity pneumonitis patients^#

Case	Smoking	Clinical presentation	Crackles	D_L,CO % pred	P_a,O₂ mmHg	HRCT scan^¶	BAL
Case	Smoking	Clinical presentation	Crackles	D_L,CO % pred	P_a,O₂ mmHg	HRCT scan^¶	Lymphocytes %	Neutrophils %	Total ×10⁴ cells·mL⁻¹
1	No	Chronic progressive	Yes	47	66	Ground glass, nodules, honeycombing and reticular patterns	61	10	41
2	Nonsmoker	Acute intermittent	No	86	ND	Normal	21	12	52
3	5 cigarettes·day⁻¹	Acute intermittent	No	65	78	Ground glass	56	10	62
4	Ex-smoker 10 pack-yrs	Acute intermittent	Yes	72	82	Normal	25	4	57
5	Nonsmoker	Acute intermittent	No	80	95	Normal	32	12	42
6	Nonsmoker	Acute intermittent	Yes	70	92	Ground glass	45	5	54
7	Nonsmoker	Acute intermittent	Yes	79	ND	Ground glass	ND	ND	ND
8	Ex-smoker 30 pack-yrs	Acute progressive	Yes	67	78	Ground glass	42	6	78
9	Ex-smoker 12 pack-yrs	Acute intermittent	Yes	76	ND	Ground glass, consolidations	ND	ND	ND
10	Nonsmoker	Acute progressive	Yes	38	63	Ground glass	70	5	66
11	Nonsmoker	Acute intermittent	Yes	68	92	Ground glass	30	6	51
12	Nonsmoker	Chronic progressive	Yes	50	86	Ground glass	56	5	55
13	55 pack-yrs	Chronic progressive	Yes	54	72	Ground glass	23	3	67

D_L,CO: diffusing capacity of the lung for carbon monoxide; % pred: % predicted; P_a,O₂: arterial oxygen tension; HRCT: high-resolution computed tomography; BAL: bronchoalveolar lavage; ND: not determinated. ^#: n = 13; ^¶: HRCT scan was perfomed 6–8 weeks after exposure in cases 2–5.