CTEPH | PAH | Total | |
Subjects | 41 | 31 | 72 |
Demographic data | |||
Age yrs | 63.0 (56.0–70.0) | 62.0 (49.0–69.0) | 63.0 (50.0–70.0) |
Ethnic origin white % | 41 (100) | 31 (100) | 72 (100) |
Females % | 18 (44) | 21 (68) | 39 (54) |
Weight kg | 75.0 (66.0–85.0) | 72.0 (63.0–86.0) | 74.0 (63.5–85.0) |
Height cm | 170.0 (165.0–174.0) | 166.0 (160.0–172.0) | 169.5 (163.5–174.0) |
Body mass index kg·m−2 | 24.7 (23.3–28.1) | 25.8 (23.4–30.5) | 24.8 (23.4–29.3) |
Functional status | |||
WHO functional class | |||
I | 0 (0) | 0 (0) | 0 (0) |
II | 10 (24) | 5 (16) | 15 (21) |
III | 31 (76) | 25 (81) | 56 (78) |
IV | 0 (0) | 1 (3) | 1 (1) |
6-min walk distance m | 390.0 (330.0–441.0) | 337.0 (215.0–406.0) | 359.0 (300.0–420.0) |
Right heart catheterisation | |||
Mean pulmonary arterial pressure mmHg | 44.0 (38.0–51.0) | 48.0 (36.0–55.0) | 45.5 (38.0–53.0) |
Pulmonary vascular resistance dyn·s·cm−5 | 686 (516–859) | 836 (511–1173) | 727 (513–996) |
Pulmonary capillary wedge pressure mmHg | 8.0 (5.0–12.0) | 8.0 (5.0–10.0) | 8.0 (5.0–11.0) |
Systemic vascular resistance# dyn·s·cm−5 | 1721 (1346–2067) | 1744 (1456–2275) | 1730 (1368–2143) |
Cardiac index L·min−1·m−2 | 2.31 (1.94–2.68) | 2.13 (1.84–2.50) | 2.19 (1.92–2.54) |
Pulmonary/systemic vascular resistance# % | 44.1 (34.3–50.2) | 48.0 (32.2–58.7) | 45.7 (33.3–52.4) |
Data are presented as n, n (%) or median (interquartile range). CTEPH: chronic thromboembolic pulmonary hypertension; PAH: pulmonary arterial hypertension; WHO: World Health Organization. #: measurements required to calculate baseline systemic vascular resistance were available for 66 patients (CTEPH n = 40; PAH n = 26).