Table 3– Univariate analysis (Chi-squared test, ANOVA test) of the underlying conditions, clinical presentation, complications and outcome for 294 patients according the presence of several groups of serotypes
H serotypesL serotypesO serotypes
Subjects9378123
Age yrs54.2±20.066.4±17.265.2±18.5
Comorbidities
 Cardiopathy10 (10.7)+23 (29.4)30 (24.3)
 Lung Disease18 (19.3)§21 (26.9)44 (35.7)
 Liver disease7 (7.5)+15 (19.2)24 (19.5)
 Renal disease5 (5.3)7 (8.9)16 (13)
 Immunocompromise6 (6.4)12 (15.3)20 (16.2)
Charlson score1.04±1.62.44±2.32.49±2.2
Pa,O2/FI,O2 <25024 (25.8)35 (44.8)##42 (34)
Need for vasopressors15 (16.1)21 (26.9)##13 (10.5)
Multilobar involvement42 (45.1)42 (53.8)46 (37.3)
ICU admission20 (21.5)25 (32)24 (19.5)
Mechanical ventilation12 (12.9)20 (25.6)##17 (13.8)
Severe pneumonia#25 (26.8)40 (51.2)##43 (34.9)
Pleural effusion33 (35.4)23 (29.4)32 (26)
Complicated parapneumonic effusion or empyema16 (17.2)5 (6.4)5 (4)
Combination therapy44 (47)49 (63)63 (51)
PSI class V17 (18.2)ƒ47 (60.2)49 (39.8)
LOS for survivors12.72±12.117.2±16.714.21±11.1
30-day mortality3 (3.2)20 (25.6)¶¶9 (7.3)
  • Data are presented as n, mean±sd or n (%), unless otherwise stated. H serotypes: 1, 5 and 7 F. L serotypes: 3, 6A, 6B, 8, 19F and 23F. O: Other serotypes. Pa,O2: arterial oxygen tension; FI,O2: inspiratory oxygen fraction; ICU: intensive care unit; PSI: Pneumonia Severity Index; LOS: length of stay. #: Pneumonia was considered severe when patients met at least one of two major American Thoracic Society (ATS)/Infectious Diseases Society of America (IDSA) criteria or three of the nine minor ATS/IDSA criteria 1. : p<0.001 between group H and the other two groups. +: p<0.05 between group H and the other two groups (Chi-squared test). §: p<0.05 between groups H and O. ƒ: p<0.05 between three groups. ##: p<0.05 between group L and the other two groups. ¶¶: p<0.001 between group L and the other two groups.