Table 4– Association of the rs13118928 single nucleotide polymorphism# with chronic obstructive pulmonary disease: results of the meta-analysis
SampleOR (95% CI)p-value
Rotterdam Study0.81 (0.72–0.91)<0.001
Bergen cohort0.73 (0.62–0.86)<0.001
NETT/NAS0.71 (0.56–0.88)0.002
Overall0.77 (0.70–0.84)3.43×10−9

  • Logistic regression models, adjusted for age, sex, smoking behaviour and the number of pack-years of smoking, were used for the analyses. NETT: National Emphysema Treatment Trial; NAS: Normative Aging Study. #: near the Hedgehog-interacting protein gene; : data from 18.