Table 1– Demographic, lung function, exercise tolerance and quality of life assessment of non-cachectic and cachectic chronic obstructive pulmonary disease patients
Non-cachecticCachectic
Subjects n1910
Age yrs67±263±2
Weight kg77±360±3*
BMI kg·m−227.8±1.221.5±0.7*
FFM index kg·cm−219.0±0.415.6±0.4*
FEV1 L1.18±0.120.98±0.14
FEV1 % pred44.1±4.837.5±6.1
FVC L2.84±0.192.49±0.17
FVC % pred80.0±5.272.9±6.0
TLC % pred108.7±5.5126.2±7.9
FRC % pred152.3±10.5172.6±12.4
RV % pred147.6±21.1178.7±40.8
TL,CO% pred51.3±5.642.8±4.9*
Peak WR W53±443±6*
Peak V′O2 mL·kg−1·min−115±0.9714.1±1.62
6-min walking distance m344±21273±44*
SGRQ total score45.22±3.7140.97±4.99*

  • Data are presented as mean±sem, unless otherwise stated. BMI: body mass index; FFM: fat-free mass; FEV1: forced expiratory volume in 1 s; % pred: % predicted; FVC: forced vital capacity; TLC: total lung capacity; FRC: functional residual capacity; RV: residual volume; TL,CO: transfer factor of the lung for carbon monoxide; WR: work rate; V′O2: oxygen uptake; SGRQ: St George’s Respiratory Questionnaire. *: p<0.05 compared with non-cachectic patients (unpaired t-test).