Table 4—

Patterns of variables of subjects with full data set# defined by the agnes method

Cluster
12345
Pre-BD FEV1/FVC %--+/-+/-+/-
Pre-BD FEV1 % pred----+/-+/-+/-
Reversibility %+ +--+--+
DL,CO/VA % pred----+/-+/-+/-
FRC % pred+ +++/-+/-+/-
Log IgE g·L−1+ +--+ ++/-+/-
FeNO ppb+/---+ +--+/-
Sputum production %100000100
Smoking history pack-yrs+ +++------
  • BD: bronchodilator; FEV1: forced expiratory volume in 1 s; FVC: forced vital capacity; % pred: % predicted; DL,CO: diffusing capacity of the lung for carbon monoxide; VA: alveolar volume; FRC: functional residual capacity; Ig: immunoglobulin; FeNO: exhaled nitric oxide fraction. --: ≥20% below mean; -: ≥10% and <20% below mean; +/-: within 10% of mean; +: ≥10% and <20% above mean; ++: ≥20% above mean. #: n = 175; : adjusted for haemoglobin concentration.