Baseline pharmacodynamic characteristics in study part B
| Parameter | Riociguat | |
| 1 mg | 2.5 mg | |
| Subjects n | 5 | 10 |
| mPAP mmHg | 55.4±16.6 | 42.1±11.3 |
| PVR dyn·s·cm−5 | 1028±491 | 566±209 |
| SBP mmHg | 147±25 | 133±20 |
| SVR dyn·s·cm−5 | 2127±407 | 1324±335 |
| Cardiac index L·min−1·m−2 | 2.17±0.18 | 2.74±0.82 |
| Heart rate beats·min−1 | 84±12 | 73±10 |
mPAP: mean pulmonary arterial pressure; PVR: pulmonary vascular resistance; SBP: systolic blood pressure; SVR: systemic vascular resistance.