Prevalence ofChlamydia in inflammatory and noninflammatory airway disease
| Inflammatory airway disease | Noninflammatory airway disease | Elevated serum IgE | Normal serum IgE | |
| Subjects | 150 | 32 | 72 | 110 |
| Chlamydia culture positive | 69 (46)# | 6 (18)# | 43 (60) | 81 (74) |
| Chlamydia DNA positive | 104 (69.3) | 20 (62.5) | 26 (36) | 49 (45) |
Data are presented as n or n (%). Inflammatory airway disease included asthma, pneumonia and bacterial bronchitis; noninflammatory diseases included gastro-oesophageal reflux disease, aspirations, laryngomalacia, dyspnoea, structural anomalies, chronic cough and vascular compression. #: p = 0.005, Fisher’s exact test (two-sided). There was no significant association with PCR-positive samples (p = 0.531). There was no statistically significant association between patients with elevated serum immunoglobulin (Ig)E and the presence of Chlamydia DNA or cultivable organisms.