Table 1—

Main clinical, functional and bronchoalveolar fluid(BALF) data

Never-smokersSmokers with normal lung functionCOPD patients
Subjects n91010
Age yrs56±560±364±2*
Smoking history pack-yrs037±545±3
FEV1# % pred103±1698±1058±6*
FEV1 FVC %79±1178±657±7*
Total cell count 103·mL−165.6±17.6271±58*182±33*
Macrophages %92±192±285±3
Lymphocytes %7±17±29±2
Neutrophils %1±0.41±0.23±2
BALF recovery m105±794±470±7*
  • Data are presented as mean±sem, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity. #: measured after bronchodilation. *: p<0.05 versus never-smokers.