Never-smokers | Smokers with normal lung function | COPD patients | |
Subjects n | 9 | 10 | 10 |
Age yrs | 56±5 | 60±3 | 64±2* |
Smoking history pack-yrs | 0 | 37±5 | 45±3 |
FEV1# % pred | 103±16 | 98±10 | 58±6* |
FEV1 FVC % | 79±11 | 78±6 | 57±7* |
Total cell count 103·mL−1 | 65.6±17.6 | 271±58* | 182±33* |
Macrophages % | 92±1 | 92±2 | 85±3 |
Lymphocytes % | 7±1 | 7±2 | 9±2 |
Neutrophils % | 1±0.4 | 1±0.2 | 3±2 |
BALF recovery m | 105±7 | 94±4 | 70±7* |
Data are presented as mean±sem, unless otherwise stated. COPD: chronic obstructive pulmonary disease; FEV1: forced expiratory volume in one second; % pred: % predicted; FVC: forced vital capacity. #: measured after bronchodilation. *: p<0.05 versus never-smokers.