Multivariate analysis of delayed normalisation of C-reactive protein (CRP) and the risk for having an unfavorable outcome
| Mortality (within 28 day) | Early (within 3 days) treatment failure | Late (within 28 days) treatment failure | ||||
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Day 0–3 CRP decline <60% | 1.09 (0.32–3.73) | 0.89 | 1.57 (0.85–2.92) | 0.16 | 1.29 (0.62–2.68) | 0.50 |
| Day 0–7 CRP decline <90% | 1.23 (0.45–2.99) | 1.00 | 0.87 (0.39–1.94) | 0.74 | ||
The displayed odds ratios (ORs) are adjusted for patient characteristics (age, sex and comorbid illnesses), Pneumonia Severity Index score, symptoms and signs of pneumonia (cough, sputum production, sore throat, dyspnoea, chest pain, hemoptoe, confusion, blood pressure, respiratory rate, pulse and oxygen saturation). CI: confidence interval.