Biomarker power calculations
| Biomarker | Between-subject sd | Power calculation | ||
| Effect size | Subjects needed per group n | |||
| 80% power | 90% power | |||
| EBC pH | 0.99 | 2.00 | 5 | 6 |
| 0.75 | 30 | 40 | ||
| 0.30 | 175 | 225 | ||
| EBC 8-isoprostane pg·mL−1 | 37.6 | 25 | 50 | 35 |
| 10 | 200 | 250 | ||
| 4 | >300 | >300 | ||
| EBC LTB4 pg·mL−1 | 11.6 | 16 | 10 | 12 |
| 6 | 60 | 80 | ||
EBC: exhaled breath condensate; LT: leukotriene.