OSA group | Control group | p-value# | |
Subjects n | 30 | 15 | |
Age yrs | 52±13 | 48±10 | 0.292 |
Height cm | 171±7 | 173±5 | 0.264 |
Weight kg | 89±14 | 86±16 | 0.546 |
BMI kg·m−2 | 30.5±4.0 | 28.7±4.7 | 0.188 |
Current smokers % | 37 | 27 | 0.374 |
Smoking history pack-yrs | 20±12 | 20±7 | 0.965 |
AHI events·h−1 | 43.8±27.0 | 3.7±3.3 | 0.000 |
AI events·h−1 | 29.4±26.4 | 1.0±0.8 | 0.005 |
Obstructive events % | 96±6 | 66±31 | 0.000 |
Total sleep study time <90% Sa,O2 % | 18.41±23.39 | 0.04±0.05 | 0.000 |
ODI events·h−1 | 44.6±26.7 | 4.7±3.8 | 0.000 |
Mean nocturnal Sa,O2% | 91±6 | 94±2 | 0.024 |
Minimum Sa,O2% | 72±15 | 85±5 | 0.016 |
FVC % pred | 105±17 | 99±16 | 0.313 |
FEV1 % pred | 111±15 | 108±16 | 0.500 |
FEV1/FVC % | 85.8±7.2 | 88.2±3.6 | 0.156 |
Daytime SBP mmHg | 126±10 | 122±9 | 0.154 |
Daytime DBP mmHg | 79±6 | 78±5 | 0.529 |
Daytime MBP mmHg | 95±7 | 92±6 | 0.208 |
Night-time SBP mmHg | 117±11 | 110±10 | 0.059 |
Night-time DBP mmHg | 70±7 | 67±6 | 0.127 |
Night-time MBP mmHg | 86±8 | 82±8 | 0.058 |
Diurnal norepine µg·g−1 | 34.9±13.1 | 29.9±11.6 | 0.211 |
Diurnal epine µg·g−1 | 7.0±4.9 | 7.9±4.5 | 0.571 |
Nocturnal norepine µg·g−1 | 21.9±12.1 | 12.9±6.2 | 0.002 |
Nocturnal epine µg·g−1 | 6.5±5.3 | 4.2±2.4 | 0.049 |
Norepine nocturnal dip % | 36±27 | 48±24 | 0.182 |
Epine nocturnal dip % | 16±10 | 32±46 | 0.039 |
Heart rate beats·min−1 | 76±13 | 78±11 | 0.640 |
LVDD mm | 52.1±2.8 | 50.7±5.8 | 0.399 |
LVSD mm | 32.5±2.5 | 30.3±4.8 | 0.060 |
Posterior wall mm | 10.6±1.2 | 9.3±1.4 | 0.004 |
Interventricular septum mm | 10.7±1.1 | 9.5±1.5 | 0.009 |
Left ventricular mass g | 213.4±38.0 | 178.3±39.5 | 0.007 |
Left ventricular mass index g·m−2 | 107.0±19.6 | 89.5±17.6 | 0.007 |
LVSF % | 37.6±3.1 | 40.1±4.8 | 0.076 |
LVEF % | 67.1±3.7 | 70.1±5.9 | 0.084 |
Left atrial diameter mm | 37.6±3.6 | 36.1±5.6 | 0.363 |
Data are expressed as mean±sd, unless otherwise stated. BMI: body mass index; AHI: apnoea/hypopnoea index; AI: apnoea index; Sa,O2: arterial oxygen saturation; ODI: oxygen desaturation index; FVC: forced vital capacity; % pred: % predicted; FEV1: forced expiratory volume in one second; SBP: systolic blood pressure; DBP: diastolic blood pressure; MBP: mean blood pressure; norepine: norepinephrine; epine: epinephrine; LVDD: left ventricular diastolic diameter; LVSD: left ventricular systolic diameter; LVSF: left ventricular shortening fraction; LVEF: left ventricular ejection fraction. #: Wilcoxon test.